N-LAUROYL-D-ERYTHRO-SPHINGOSINE
Synonym(s):C12 Ceramide (d18:1/12:0);C12-Ceramide;Cer(d18:1/12:0);N-(dodecanoyl)-sphing-4-enine;N-lauroyl-D-erythro-sphingosine
- CAS NO.：74713-60-3
- Empirical Formula: C30H59NO3
- Molecular Weight: 481.79
- MDL number: MFCD02259133
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:25:40
What is N-LAUROYL-D-ERYTHRO-SPHINGOSINE?
Chemical properties
white powder
The Uses of N-LAUROYL-D-ERYTHRO-SPHINGOSINE
Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. N-Acyl chain length of membrane ceramides can influence bidimensional transitions, condensed domain morphology, and interfacial thickness.
The Uses of N-LAUROYL-D-ERYTHRO-SPHINGOSINE
C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:
- as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
- as an internal standard for lipid extraction in U87MG (human glioma cell line)
- as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues
Definition
ChEBI: N-dodecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as dodecanoyl (lauroyl). It is functionally related to a dodecanoic acid.
General Description
Ceramide is a sphingolipid with long acyl chain attached to a fatty. It is synthesized in the endoplasmic reticulum by ceramide synthase.
Biochem/physiol Actions
Ceramides?are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis.
Properties of N-LAUROYL-D-ERYTHRO-SPHINGOSINE
| Melting point: | 70 - 72°C |
| Boiling point: | 579.38°C (rough estimate) |
| Density | 0.9777 (rough estimate) |
| refractive index | 1.6310 (estimate) |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated, Sonicat |
| form | Solid |
| pka | 13.54±0.20(Predicted) |
| color | White to Off-White |
| BRN | 1717021 |
Safety information for N-LAUROYL-D-ERYTHRO-SPHINGOSINE
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-LAUROYL-D-ERYTHRO-SPHINGOSINE
New Products
Paroxetine Impurity G/Paroxetine Related Compound E 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) 1-aminocyclopentane carbonitrile, HCl H-D-TRP(FOR)-OH HCL 9-Mesityl-10-methylacridinium perchlorate 3-Amino-3-(4-fluorophenyl)propanoic acid Benzyl (3R,4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylate Bisacodyl Related Compound C/Bisacodyl EP Impurity C Levothyroxine Beta Hydroxy Impurity Candesartan EP Impurity-F/Candesartan Cilexetil USP Related Compound F / Candesartan Cilexetil N2-Ethyl Impurity / 2H-N2-Ethyl Candesartan Cilexetil Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Sumatriptan Succinate USP Related Compound C N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecarboxamide N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide L-phenylalanine methyl ester hydrochloride 2,2'-(5-Bromomethyl-1,3-phenylene)-di(2-Methylpropionitrile) tri sodium thio phosphate L-phenylalanine, N-(pyrazinyl carbonyl) methyl ester 3-chlorobenzyl cyanide 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 4-Bromo Benzylcyanide 3-Hydroxypropionitrile valeronitrileRelated products of tetrahydrofuran
![N-OCTANOYL-D-ERYTHRO-DIHYDROSPHINGOSINE [4,5-3H] 1-PHOSPHATE](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB8668493.gif)
You may like
-
C12 Ceramide CAS 74713-60-3View Details
74713-60-3 -
C12 Ceramide (d18:1/12:0) CAS 74713-60-3View Details
74713-60-3 -
2847776-12-7 Sumatriptan Succinate USP Related Compound C NLT 95%View Details
2847776-12-7 -
1012886-75-7(HCl Salt)/69675-10-1(Freebase) Paroxetine Impurity G/Paroxetine Related Compound E NLT 95%View Details
1012886-75-7(HCl Salt)/69675-10-1(Freebase) -
93-17-4 99%View Details
93-17-4 -
1529-41-5 3-chlorobenzyl cyanide 99%View Details
1529-41-5 -
2856-63-5 99%View Details
2856-63-5 -
3,4 Diethoxy Benzylcyanide 99%View Details
27472-21-5
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.