N-Isopropylmethylamine
Synonym(s):N-Methylisopropylamine
- CAS NO.:4747-21-1
- Empirical Formula: C4H11N
- Molecular Weight: 73.14
- MDL number: MFCD00042859
- EINECS: 225-266-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:26:24
What is N-Isopropylmethylamine?
Chemical properties
Colorless to light yellow liqui
The Uses of N-Isopropylmethylamine
N-Isopropylmethylamine is used in the generation of in situ micelles having distinct sizes, by sequential self-assembly of a series of stimuli-responsive amphiphilic block copolymers, prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization. It is suitable for use in the synthesis of novel 5-ethoxy-N,N-dialkyl-[α,α,β,β-H4]-tryptamines and their [α,α,β,β,β-D4]-counterparts following the Speeter and Anthony procedure.
What are the applications of Application
N-Isopropylmethylamine is suitable for use in the generation of in situ micelles having distinct sizes, by sequential self-assembly of a series of stimuli-responsive amphiphilic block copolymers, prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization. It is suitable for use in the synthesis of novel 5-ethoxy-N,N-dialkyl-[α,α,β,β-H4]-tryptamines and their [α,α,β,β,β?D4]-counterparts following the Speeter and Anthony procedure.
General Description
N-Isopropylmethylamine is an unsymmetrical amine. Pd/C-catalyzed oxidative cross double carbonylation of N-isopropylmethylamine with alcohols has been reported.
Flammability and Explosibility
Highly flammable
Properties of N-Isopropylmethylamine
| Melting point: | -55.1°C (estimate) |
| Boiling point: | 50-53 °C (lit.) |
| Density | 0.702 g/mL at 25 °C (lit.) |
| vapor pressure | 4.15 psi ( 20 °C) |
| refractive index | n |
| Flash point: | −25 °F |
| storage temp. | Refrigerator, Under Inert Atmosphere |
| solubility | Soluble in chloroform, DMSO, methanol. |
| form | Liquid |
| pka | 10.76±0.10(Predicted) |
| Specific Gravity | 0.702 |
| color | Colorless |
| Sensitive | Air Sensitive |
| BRN | 1730877 |
| Stability: | Volatile |
| CAS DataBase Reference | 4747-21-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Propanamine, N-methyl-(4747-21-1) |
Safety information for N-Isopropylmethylamine
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Isopropylmethylamine
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