N-FORMYL-MET-LEU-PHE
Synonym(s):Chemotactic peptide;fMLF;fMLP (misnomer but widely used);N-Formyl-L -methionyl-L -leucyl-L -phenylalanine
- CAS NO.：5979-11-3
- Empirical Formula: C50H73N15O11.3C2H4O2
- Molecular Weight: 1240.38
- MDL number: MFCD00036780
- EINECS: 227-781-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:24
What is N-FORMYL-MET-LEU-PHE?
The Uses of N-FORMYL-MET-LEU-PHE
N-Formyl-Met-Leu-Phe is an inducer of superoxide release and agonist for FPR1.
What are the applications of Application
Bradykinin triacetate is a pro-inflammatory polypeptide
Purification Methods
Purify Bradykinin by ion-exchange chromatography on CMC (O-carboxymethyl cellulose) and partition chromatography on Sephadex G-25. The purity is checked by paper chromatography using BuOH/AcOH/H2O (4:1:5) as eluent. [Park et al. Can J Biochem 56 92 1978, ORD and CD: Bodanszky et al. Experientia 26 948 1970, activity: Regoli & Barabé Pharmacol Rev 32 1 1980, Beilstein 22 III/IV 91.]
Properties of N-FORMYL-MET-LEU-PHE
| Melting point: | 150-160℃ |
| alpha | -84.1 (D/23℃) (c=1.1, H2O)-78.4 (D/25℃) (c=1.4, 1N AcOH) |
| storage temp. | 2-8°C |
| solubility | DMF: 50 mg/mL, clear, colorless |
| form | powder |
| color | white |
| CAS DataBase Reference | 5979-11-3(CAS DataBase Reference) |
Safety information for N-FORMYL-MET-LEU-PHE
Computed Descriptors for N-FORMYL-MET-LEU-PHE
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