N-Ethyl-p-toluenesulfonamide

CAS NO.：80-39-7
Empirical Formula: C9H13NO2S
Molecular Weight: 199.27
MDL number: MFCD00048511
EINECS: 201-275-1
SAFETY DATA SHEET (SDS)
Update Date: 2026-01-13 11:27:10

What is N-Ethyl-p-toluenesulfonamide?

Chemical properties

off-white crystalline solid

The Uses of N-Ethyl-p-toluenesulfonamide

N-Ethyl-4-toluene sulfonamide is a resin carrier in dental materials used for isolating cavities below restorations; plasticizer in polyvinyl alcohollacquers, polyamides, cellulose acetate, etc.

The Uses of N-Ethyl-p-toluenesulfonamide

N-?Ethyl-?p-?toluenesulfonamide is a reagent used in the sulfonamidation of imidazopyridines.

The Uses of N-Ethyl-p-toluenesulfonamide

Plasticizer.

General Description

Platelets (from dilute alcohol or ligroin) or off-white solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

An amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Fire Hazard

Flash point data for N-Ethyl-p-toluenesulfonamide are not available; however, N-Ethyl-p-toluenesulfonamide is probably combustible.

Properties of N-Ethyl-p-toluenesulfonamide

Melting point:	63-65 °C(lit.)
Boiling point:	208 °C745 mm Hg(lit.)
Density	1.26 g/cm3
refractive index	1.5270 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	11.86±0.50(Predicted)
color	White to Off-White
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	80-39-7(CAS DataBase Reference)
NIST Chemistry Reference	4-Toluenesulfonamide, n-ethyl-(80-39-7)
EPA Substance Registry System	N-Ethyl-p-toluenesulfonamide (80-39-7)

Safety information for N-Ethyl-p-toluenesulfonamide

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.