N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
- CAS NO.:110025-28-0
- Empirical Formula: C25H27NO2
- Molecular Weight: 373.49
- MDL number: MFCD09840374
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-27 18:41:44
What is N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)?
Chemical properties
Brown Foam
The Uses of N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca
The Uses of N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.
What are the applications of Application
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) is novel active metabolite of the anti-cancer drug Tamoxifen
Storage
Store at +4°C
Properties of N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
| Melting point: | 63-72°C |
| Boiling point: | 519.3±50.0 °C(Predicted) |
| Density | 1.099±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | Chloroform, Dichloromethane, DMSO, Methanol |
| form | Solid |
| pka | 9.38±0.15(Predicted) |
| color | Light Brown to Light Purple |
Safety information for N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H332:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P330:Rinse mouth. P361:Remove/Take off immediately all contaminated clothing. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
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