N-Benzoyl-2'-deoxy-adenosine
- CAS NO.：4546-72-9
- Empirical Formula: C17H17N5O4
- Molecular Weight: 355.35
- MDL number: MFCD00009628
- EINECS: 224-903-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:31
What is N-Benzoyl-2'-deoxy-adenosine?
Description
N-Benzoyl-2'-deoxyadenosine is a nucleoside analog that is used in the diagnosis of infections caused by bacteria. N-Benzoyl-2'-deoxyadenosine binds to DNA duplexes and alters their structure, which can be detected using electrophoresis. N-Benzoyl-2'-deoxyadenosine has been shown to have low bioavailability and is insoluble in water, so it must be administered intravenously. It has also been found to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.
The Uses of N-Benzoyl-2'-deoxy-adenosine
Reactant in the synthesis of 2', 5'-Dideoxycytidines and Other Derivatives of 2'-Deoxycytidine. Reactant in the synthesis of Mono- and Diamino Analogues of 2?-Deoxyadenosine, Cordycepin, 9-(3-Deoxy-α-D-Threo-Pentofuranosyl)-Adenine and 9-(2-Deoxy-α-D-Threo-Pentofuranosyl)Adenine.
Properties of N-Benzoyl-2'-deoxy-adenosine
| Melting point: | 120-122C |
| Density | 1.61±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:6): 0.14 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml |
| form | A crystalline solid |
| pka | 7.87±0.43(Predicted) |
| Water Solubility | Soluble in water (slightly), and methanol (20 mg/ml). |
| CAS DataBase Reference | 4546-72-9(CAS DataBase Reference) |
Safety information for N-Benzoyl-2'-deoxy-adenosine
Computed Descriptors for N-Benzoyl-2'-deoxy-adenosine
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