N-Acetyl-L-cysteine ethyl ester
- CAS NO.：59587-09-6
- Empirical Formula: C7H13NO3S
- Molecular Weight: 191.25
- MDL number: MFCD09954466
- EINECS: 000-000-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-02-24 17:00:29
What is N-Acetyl-L-cysteine ethyl ester?
Description
N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; ). It has enhanced cell permeability in isolated perfused rat liver compared to NAC. N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; ) in rats.
Properties of N-Acetyl-L-cysteine ethyl ester
| Melting point: | 44.1-44.5 °C |
| Boiling point: | 337.6±32.0 °C(Predicted) |
| Density | 1.138±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml |
| pka | 9.17±0.10(Predicted) |
| form | A crystalline solid |
| color | White to off-white |
Safety information for N-Acetyl-L-cysteine ethyl ester
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H372:Specific target organ toxicity, repeated exposure H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P501:Dispose of contents/container to..… |
Computed Descriptors for N-Acetyl-L-cysteine ethyl ester
New Products
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![N-ACETYL-S-[3-(D-3)-ACETAMINO-6-HYDROXPHENYL]-CYSTEINE ALLYL ESTER, DEUTERATED](https://img.chemicalbook.in/)
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