N-Acetyl-4-piperidone
- CAS NO.：32161-06-1
- Empirical Formula: C7H11NO2
- Molecular Weight: 141.17
- MDL number: MFCD00006190
- EINECS: 250-937-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is N-Acetyl-4-piperidone?
Chemical properties
clear orange oily liquid
The Uses of N-Acetyl-4-piperidone
1-Acetyl-4-piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs, and manufacture of fentanyl.
Purification Methods
Purify it by fractional distillaton through a short Vigreux column (15mm, p 11). The 2,4-dinitrophenylhydrazone has m 212-213o (from EtOH). It is freely soluble in H2O but insoluble in Et2O. [McElvain & McMahon J Am Chem Soc 71 901 1949, Beilstein 21/6 V 246.]
Properties of N-Acetyl-4-piperidone
| Boiling point: | 218 °C(lit.) |
| Density | 1.146 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Oily Liquid |
| pka | -0.72±0.20(Predicted) |
| Specific Gravity | 1.16 |
| color | Clear orange |
| Water Solubility | Soluble in water. Insoluble in acetic acid. |
| BRN | 116031 |
| CAS DataBase Reference | 32161-06-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Acetyl-4-piperidone(32161-06-1) |
Safety information for N-Acetyl-4-piperidone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Acetyl-4-piperidone
N-Acetyl-4-piperidone manufacturer
JSK Chemicals
2Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 32161-06-1 1-Acetyl-4-piperidone, 95% 99%
SAKEM LLP
1Y
Phone:+91-9676889998
Whatsapp: +91-9676889998
product: 32161-06-1 1-Acetyl-4-Piperidone 98%
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: N-Acetyl-4-piperidone
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