N-(4,6,7-TRIMETHYLQUINAZOLIN-2-YL)GUANIDINE
- CAS NO.：784-90-7
- Empirical Formula: C12H15N5
- Molecular Weight: 229.28
- MDL number: MFCD00981386
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is N-(4,6,7-TRIMETHYLQUINAZOLIN-2-YL)GUANIDINE?
Definition
ChEBI: 2-(4,6,7-Trimethyl-2-quinazolinyl)guanidine is a member of quinazolines.
Biological Activity
A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively[1].
References
[1]. Thomas R Webb, et al. Quinazolines as adenosine receptor antagonists: SAR and selectivity for A2B receptors. Bioorg Med Chem. 2003 Jan 2;11(1):77-85.
Properties of N-(4,6,7-TRIMETHYLQUINAZOLIN-2-YL)GUANIDINE
| Melting point: | 259-260 °C (decomp) |
| Boiling point: | 435.9±55.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | 4°C, protect from light |
| solubility | Methanol : 5 mg/mL (21.81 mM; ultrasonic and warming and heat to 60°C)|DMSO : 2 mg/mL (8.72 mM; ultrasonic and warming and heat to 60°C) |
| pka | 8.13±0.30(Predicted) |
| form | Solid |
| color | White to off-white |
Safety information for N-(4,6,7-TRIMETHYLQUINAZOLIN-2-YL)GUANIDINE
Computed Descriptors for N-(4,6,7-TRIMETHYLQUINAZOLIN-2-YL)GUANIDINE
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) Cis-Tosylate Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) BOC Piperazine 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) TERTIARY BUTANOL-D9 N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D TOLUENE-D3 Trans,trans muconic acid HC Blue-16 4-Amino-2-chloro-6,7-dimethoxyquinazoline Ethyl 4,5-bis(2-methoxyethoxy)-2-nitrobenzoate 2,3-Dimethoxypyridine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
N-(4,6,7-Trimethylquinazolin-2-yl)guanidine 95% CAS 784-90-7View Details
784-90-7 -
Product IntroductionView Details -
Product InrtroductionView Details -
DGO24View Details -
DGO25View Details -
DGO29View Details -
DGO32View Details -
DGO36View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.