N-(4-Hydroxymethylbenzyl) Cyclam
- CAS NO.：176252-20-3
- Empirical Formula: C18H32N4O
- Molecular Weight: 320.47
- Update Date: 2022-12-21 16:56:50
What is N-(4-Hydroxymethylbenzyl) Cyclam?
The Uses of N-(4-Hydroxymethylbenzyl) Cyclam
N-(4-Hydroxymethylbenzyl) Cyclam is an impurity of Plerixafor (P580500), a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin''s lymphoma (NHL) and multiple myeloma (MM).
Properties of N-(4-Hydroxymethylbenzyl) Cyclam
| Boiling point: | 496.9±45.0 °C(Predicted) |
| Density | 1.002±0.06 g/cm3(Predicted) |
| pka | 14.44±0.10(Predicted) |
Safety information for N-(4-Hydroxymethylbenzyl) Cyclam
Computed Descriptors for N-(4-Hydroxymethylbenzyl) Cyclam
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