N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
- CAS NO.：2098488-36-7
- Empirical Formula: C19H20N6O6
- Molecular Weight: 428.3987
- MDL number: MFCD31560486
- Update Date: 2026-08-11 13:38:40
What is N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide?
Description
UUN 88367, also known as Azido-Thalidomide is a clickable Thalidomide derivative, used as a building block for cereblon. Azido-Thalidomide targets PROTACs by hijacking cereblon as the E3 ubiquitin ligase component. This product has no formal name at the moment.
Storage
Store at -20°C
Properties of N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
| solubility | DMF: 12 mg/ml; DMSO: 12 mg/ml; DMSO:PBS (pH 7.2)(1:8): 0.11 mg/ml |
| form | A crystalline solid |
| color | White to off-white |
Safety information for N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
Computed Descriptors for N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
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![Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-](https://img.chemicalbook.in/CAS/20210111/GIF/2360527-40-6.gif)
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