Ethyl 3-(pyridin-2-ylamino)propanoate
- CAS NO.：103041-38-9
- Empirical Formula: C10H14N2O2
- Molecular Weight: 194.23
- MDL number: MFCD09833621
- EINECS: 600-382-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-18 11:52:23
What is Ethyl 3-(pyridin-2-ylamino)propanoate?
Chemical properties
White Solid
The Uses of Ethyl 3-(pyridin-2-ylamino)propanoate
Ethyl 3-(2-Pyridylamino)propanoate is an intermediate used in the synthesis of Dabigatran etexilate, as thrombin inhibitors. Ethyl Ester form of P993315.
Synthesis
A method for preparing Ethyl 3-(pyridin-2-ylamino)propanoate comprises the following steps: using 2-aminopyridine and ethyl acrylate as raw materials, using anhydrous ethanol as a solvent, using trifluoromethanesulfonic acid as a catalyst, and heating in an oil bath to control the temperature at 120 to 160° C. for a catalytic reaction for 16 to 20 hours under nitrogen protection. The obtained reaction solution is washed with petroleum ether at a temperature of 35 to 40° C. and a pressure of 0.09 to 0.1 MPa, then concentrated under reduced pressure, and then washed with petroleum ether/ethyl acetate and recrystallized to obtain white flaky crystals of Ethyl 3-(pyridin-2-ylamino)propanoate.
Properties of Ethyl 3-(pyridin-2-ylamino)propanoate
| Melting point: | 48-50°C |
| Boiling point: | 125°C/0.2mmHg(lit.) |
| Density | 1.131±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | DMSO, Methanol |
| form | Solid |
| pka | 6.26±0.10(Predicted) |
| color | White |
| InChI | InChI=1S/C10H14N2O2/c1-2-14-10(13)6-8-12-9-5-3-4-7-11-9/h3-5,7H,2,6,8H2,1H3,(H,11,12) |
Safety information for Ethyl 3-(pyridin-2-ylamino)propanoate
Computed Descriptors for Ethyl 3-(pyridin-2-ylamino)propanoate
| InChIKey | UITNIDFEANEWPC-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)CCNC1C=CC=CN=1 |
Ethyl 3-(pyridin-2-ylamino)propanoate manufacturer
Navone Specialties (OPC) Pvt Ltd
SRINI PHARMACEUTICALS PVT LTD
NSR Amino Organics
ELIXIR PHARMA
New Products
4-Nitrobenzoic acid p-Tolualdehyde 4-Chlorobenzaldehyde 2-Fluorobenzaldehyde Diethylene glycol monomethyl ether 3-Chlorobenzaldehyde N5-(2-aminoethyl)pyridine-2,5-diamine hydrochloride Ornidazole EP impurity C N-Nitroso Desloratadine Domperidone Impurity Valsartan Desalkyl Clomiphene benzophenone analog 3-(2-Chloroacetyl)pyridine hydrochloride 5,7-Dichloro-3H-Imidazo(4,5b)Pyridine 4-Piperidinecarboxylic Acid Ethyl Ester 2-Chloro-3-Fluoro-4-Iodopyridine 5-Amino-2,4-dichloropyridine 3,5-Dibromo-2-NitropyridineRelated products of tetrahydrofuran
![3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-PROPIONIC ACID ETHYL ESTER](https://img.chemicalbook.in/CAS/GIF/212322-56-0.gif)
![ETHYL N-[4-(METHYLAMINO)-3-NITROBENZOYL]-N-PYRIDIN-2-YL-SS-ALANINATE](https://img.chemicalbook.in/CAS/GIF/429659-01-8.gif)
![3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester](https://img.chemicalbook.in/CAS2/GIF/211915-84-3.gif)
![N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]arbonyl]-N-2-pyridinyl-beta-alanine ethyl ester 4-methylbenzenesulfonate](https://img.chemicalbook.in/CAS/GIF/872728-85-3.gif)
You may like
-
103041-38-9 ethyl 3-(pyridin-2-ylamino)propanoate 98%View Details
103041-38-9 -
Ethyl 3-(2-Pyridylamino) Propionate 103041-38-9 99%View Details
103041-38-9 -
Ethyl 3-(Pyridin-2-ylamino)-propionoate 98%View Details -
Ethyl 3-(Pyridin-2-ylamino)-propionoate 98%View Details -
Ethyl 3-(Pyridin-2-ylamino)-propionoate 103041-38-9 98%View Details
103041-38-9 -
103041-38-9 98%+View Details
103041-38-9 -
Ethyl 3-(2-Pyridylamino)propionate CAS 103041-38-9View Details
103041-38-9 -
N-2-Pyridinyl-beta-alanine ethyl ester 99% (GC) CAS 103041-38-9View Details
103041-38-9