Mutant IDH1 inhibitor

CAS NO.：1429180-08-4
Empirical Formula: C25H34N6O3
Molecular Weight: 466.58
Update Date: 2026-04-21 17:10:26

What is Mutant IDH1 inhibitor?

Description

Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM.

in vitro

In Vitro:Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer[1].

References

References:[1]. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404

Properties of Mutant IDH1 inhibitor

storage temp.	Store at -20°C
solubility	DMSO: ≥ 34 mg/mL (72.87 mM)
form	Powder
color	White to light yellow

Safety information for Mutant IDH1 inhibitor

Computed Descriptors for Mutant IDH1 inhibitor

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