mPEG11-Br
- CAS NO.：1258596-39-2
- Empirical Formula: C23H47BrO11
- Molecular Weight: 579.52
- MDL number: MFCD31656939
- Update Date: 2025-10-29 15:43:00
What is mPEG11-Br?
Biological Activity
m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of mPEG11-Br
| Boiling point: | 564.5±45.0 °C(Predicted) |
| Density | 1.179±0.06 g/cm3(Predicted) |
Safety information for mPEG11-Br
Computed Descriptors for mPEG11-Br
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