monoacetylcadaverine

CAS NO.：32343-73-0
Empirical Formula: C7H16N2O
Molecular Weight: 144.21
SAFETY DATA SHEET (SDS)
Update Date: 2026-03-13 23:13:44

What is monoacetylcadaverine?

The Uses of monoacetylcadaverine

N-(5-Aminopentyl)acetamide is an acetylated polyamine, a promising biochemical marker for cancer and many other pathophysiological conditions.

Definition

ChEBI: N-acetylcadaverine is an N-substituted cadaverine that is cadaverine in which one of the amino groups has been converted to the corresponding acetamide. It has a role as a human metabolite. It is a secondary carboxamide, a primary amino compound, a member of acetamides and a N-substituted cadaverine. It is functionally related to a cadaverine. It is a conjugate base of a N-acetylcadaverine(1+).

Biological Activity

Monoacetylcadaverine is the acetylated form of the polyamine cadaverine.

in vitro

Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups which ubiquitously exists in all living organisms from bacteria to higher animals. The critical step of polyamine biosynthesis generally includes the amino acid-decarboxylating reaction to produce the primary diamines, such as cadaverine from lysine. Synthesized polyamines are implicated in a wide variety of cytoplasmic reactions such as DNA replication and protein synthesis, and are essential for proper growth and proliferation of the organisms. Cadaverine is a linear molecule that terminate at both ends with an amine functional group. These functional groups confer to the multiple positive charges at physiological pH. Cadaverine is produced through the action of basic amino acid decarboxylases and is found associated with the outer membrane molecules.

Properties of monoacetylcadaverine

Boiling point:	110°C/0.02mmHg(lit.)
Density	0.938±0.06 g/cm3(Predicted)
refractive index	1.4790-1.4830
storage temp.	-20°C
solubility	Chloroform (Slightly), Dichloromethane (Slightly)
pka	16.48±0.46(Predicted)
form	clear liquid
color	Colorless to Light yellow to Light orange
CAS DataBase Reference	32343-73-0

Safety information for monoacetylcadaverine

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to..…