MOLLUGIN
Synonym(s):6-Hydroxy-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5-carboxylic acid methyl ester;Rubimaillin
- CAS NO.：55481-88-4
- Empirical Formula: C17H16O4
- Molecular Weight: 284.31
- MDL number: MFCD02752331
- EINECS: 683-209-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 05:43:01
What is MOLLUGIN?
The Uses of MOLLUGIN
Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.
Definition
ChEBI: Rubimaillin is a benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme. It has a role as a plant metabolite, an acyl-CoA:cholesterol acyltransferase 2 inhibitor, a NF-kappaB inhibitor, an antineoplastic agent, an apoptosis inducer, a neuroprotective agent and an anti-inflammatory agent. It is a benzochromene, a methyl ester and a member of phenols.
Properties of MOLLUGIN
| Melting point: | 132～134℃ |
| Boiling point: | 453.2±45.0 °C(Predicted) |
| Density | 1.239±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| pka | 8.40±0.40(Predicted) |
| color | Yellow to Green |
Safety information for MOLLUGIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for MOLLUGIN
New Products
3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID 4-Fluorophenylglycine 1-Boc-3-(cyanomethyl)azetidine Dimedone 1-N-Boc-3-(aminoethyl)azetidine N-BOC-piperidine-4-carboxylic acid 4,6-Dichlororesorcinol 5-Amino-2-Bromo-3-Chloropyridine 2-Picolinic acid N-oxide 4-Butyl Resorcinol 2-Bromo-5-Chloropyridine 5-Bromo-2-Hydroxy-3-Nitro Pyridine 2-Amino-4-phenyl-thiazole N-(4-Bromophenyl)-2-chloroacetamide TRIFLOURO ACETICACID-D METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR BENZENE-D6 TOLUENE-D3Related products of tetrahydrofuran
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