MMP-9/MMP-13 INHIBITOR I

Synonym(s):MMP-9/MMP-13 Inhibitor I - CAS 204140-01-2 - Calbiochem;N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4-biphenylcarbonyl)piperazine-2-carboxamide

CAS NO.：204140-01-2
Empirical Formula: C25H25N3O6S
Molecular Weight: 495.55
MDL number: MFCD03453559
Update Date: 2026-05-28 03:25:59

What is MMP-9/MMP-13 INHIBITOR I?

Description

MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC₅₀s = 0.9 nM for both). It less effectively inhibits MMP-1, MMP-3, and MMP-7 (IC₅₀s = 43, 23, and 920 nM, respectively). MMP-9/MMP-13 inhibitor I has been used to elucidate the roles of MMPs in biological systems, including tumor cell invasion and pathogenesis of P. falciparum.

The Uses of MMP-9/MMP-13 INHIBITOR I

A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 and MMP-13

What are the applications of Application

MMP-9/MMP-13 inhibitor I is a piperazine-based, cell-permeable inhibitor of MMP-9 and MMP-13

What are the applications of Application

MMP-9/MMP-13 Inhibitor II is a potent inhibitor of MMP-9 and MMP-13

Properties of MMP-9/MMP-13 INHIBITOR I

Density	1.364±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO or methanol
pka	9.38±0.23(Predicted)
form	Solid
color	White to off-white
Sensitive	Light Sensitive

Safety information for MMP-9/MMP-13 INHIBITOR I

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.