MMP-9 INHIBITOR I
Synonym(s):MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem
- CAS NO.：1177749-58-4
- Empirical Formula: C27H33N3O5S
- Molecular Weight: 511.63
- MDL number: MFCD22581508
- Update Date: 2026-01-13 13:16:54
What is MMP-9 INHIBITOR I?
What are the applications of Application
MMP-9 Inhibitor I is a cell-permeable and reversible MMP-9 inhibitor
Definition
ChEBI: MMP9 inhibitor I is a hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35). It has a role as an EC 3.4.24.35 (gelatinase B) inhibitor. It is a hydroxamic acid, a tertiary amino compound, a sulfonamide and an aromatic ether.
General Description
A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 μM) and MMP-13 IC50 = 113 nM) at higher concentrations.
Biochem/physiol Actions
Primary TargetMMP-9
Properties of MMP-9 INHIBITOR I
| Density | 1.276±0.06 g/cm3(Predicted) |
| storage temp. | -20C |
| form | Off-white solid |
| pka | 8.28±0.42(Predicted) |
Safety information for MMP-9 INHIBITOR I
Computed Descriptors for MMP-9 INHIBITOR I
New Products
Mirtazapine Impurity C/Mirtazapine Lactam Impurity N,O-Dimethylhydroxylamine hydrochloride Tetrabutylammonium perchlorate N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid (R)-1-Benzyl-3-pyrrolidinecarbonitrile N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide valeronitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
![2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone](https://img.chemicalbook.in/CAS2/GIF/371242-69-2.gif)
![N-[4-[5-(1,3-BENZODIOXOL-5-YL)-3-METHOXY-1H-1,2,4-TRIAZOL-1-YL]PHENYL]-2-(PHENYLTHIO)ACETAMIDE](https://img.chemicalbook.in/CAS/GIF/853625-60-2.gif)
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