MKC8866
- CAS NO.：1338934-59-0
- Empirical Formula: C18H19NO7
- Molecular Weight: 361.35
- Update Date: 2025-12-11 16:22:15
What is MKC8866?
Biological Activity
MKC8866 (IRE1-IN-8866) is a salicylaldehyde analog, a specific IRE1α RNase inhibitor with IC50 of 0.29 μM against human IRE1α in vitro.
Properties of MKC8866
| Boiling point: | 620.0±55.0 °C(Predicted) |
| Density | 1.373±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:16.67(Max Conc. mg/mL);46.13(Max Conc. mM) |
| form | A solid |
| pka | 6.20±0.20(Predicted) |
| color | Light yellow to yellow |
Safety information for MKC8866
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for MKC8866
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