MK-677
Synonym(s):Crescendo;Ibutamoren mesylate;N-[1(R)-1,2-Dihydro-1-methanesulfonylspiro-3H-indole-3,4′-piperidin)-1′-yl]carbonyl-2-(phenylmethoxy)-ethyl-2-amino-2-methylpropanamide methanesulfonate
- CAS NO.：159752-10-0
- Empirical Formula: C28H40N4O8S2
- Molecular Weight: 624.77
- MDL number: MFCD00942284
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:19:57
What is MK-677?
The Uses of MK-677
Growth hormone releasing factor.MK-677 is a potent, non-peptide ghrelin receptor agonist.
Biochem/physiol Actions
It is also known as ibutamoren mesylate. MK-677 is a mimic of growth hormone (GH)-releasing peptide and is orally active.
Side Effects
Reported side effects of MK-677 are typically the result of unnaturally high levels of growth hormone in the body from taking too much too often, which include:
Increased appetite
Lethargy
Joint pain if you have previous medical conditions or elevated hormone levels
Insulin resistance
Possible increase in prolactin levels, which can be controlled
When dosed properly, the side effects of MK-677 are minimal to none compared to the results you get from taking it properly.
Storage
Store at -20°C
Properties of MK-677
| Melting point: | 164-170°C |
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear |
| form | powder |
| color | white to beige |
Safety information for MK-677
Computed Descriptors for MK-677
| InChIKey | DUGMCDWNXXFHDE-VZYDHVRKSA-N |
| SMILES | S(O)(=O)(=O)C.S(N1C2C=CC=CC=2C2(CCN(C(=O)[C@H](NC(=O)C(N)(C)C)COCC3C=CC=CC=3)CC2)C1)(=O)(=O)C |&1:19,r| |
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