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HomeProduct name listMIT 9952-53

MIT 9952-53

Synonym(s):2-Hexyl-1-cyclopentanone thiosemicarbazone;33M20;Block lipid transport-1;Block Lipid Transport-1, 2-Hexyl-1-cyclopentanone thiosemicarbazone, 33M20;BLT1

MIT 9952-53 Structural

What is MIT 9952-53?

The Uses of MIT 9952-53

BLT-1 may be used to study cell signaling pathways that have role in cholesterol influx and efflux.

Biochem/physiol Actions

Block lipid transport-1 (BLT-1) is a specific inhibitor of the SR-BI (Scavenger receptor, class B, type I) mediated lipid transfer. The compound inhibits both cellular selective lipid uptake of HDL cholesteryl ether and efflux of cellular cholesterol to HDL.

Properties of MIT 9952-53

Boiling point: 359.6±25.0 °C(Predicted)
Density  1.14±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  DMSO: ≥13mg/mL
form  White solid
pka 12.24±0.40(Predicted)
color  white to tan
Water Solubility  Water: < 0.1 mg/mL (insoluble)

Safety information for MIT 9952-53

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P405:Store locked up.
P501:Dispose of contents/container to..…

Computed Descriptors for MIT 9952-53

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