METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE
Synonym(s):(+)-Methyl L -β-hydroxyisobutyrate;(S)-(+)-3-Hydroxy-2-methylpropionic acid methyl ester
- CAS NO.：80657-57-4
- Empirical Formula: C5H10O3
- Molecular Weight: 118.13
- MDL number: MFCD00064520
- EINECS: 203-310-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:23:32
What is METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE?
Chemical properties
Clear colorless liquid
The Uses of METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE
Methyl (S)-(+)-3-hydroxy-2-methylpropionate is used as a starting material for the synthesis of dictyostatin, discodermolide and spongidepsin.
Properties of METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE
| Boiling point: | 74 °C/10 mmHg (lit.) |
| Density | 1.071 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 178 °F |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 14.40±0.10(Predicted) |
| form | Liquid |
| color | Colorless |
| Specific Gravity | 1.07 |
| optical activity | [α]19/D +26°, c = 4 in methanol |
| Water Solubility | Insoluble in water. Soluble in methanol. |
| BRN | 1720830 |
| CAS DataBase Reference | 80657-57-4(CAS DataBase Reference) |
Safety information for METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for METHYL (S)-(+)-3-HYDROXY-2-METHYLPROPIONATE
New Products
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