Diethyl tert-butylmalonate
- CAS NO.：759-24-0
- Empirical Formula: C11H20O4
- Molecular Weight: 216.27
- MDL number: MFCD00009152
- EINECS: 212-067-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:43
What is Diethyl tert-butylmalonate?
The Uses of Diethyl tert-butylmalonate
Diethyl tert-butylmalonate is used in the preparation of enantiomers of 4-tert-butyl-3-isopropyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane 1-sulfide.
Purification Methods
Dissolve it in Et2O, wash with aqueous NaHCO3, H2O, dry (MgSO4), filter, evaporate and distil the residue. Identify by hydrolysis to the acid and determine the neutralisation equivalent (theor: 80.0). The acid has m 155-157o effervescence [Hauser et al. J Am Chem Soc 64 2715 1942, Bush & Beauchamp J Am Chem Soc 75 2949 1953]. [Beilstein 2 IV 2027.]
Properties of Diethyl tert-butylmalonate
| Boiling point: | 102-104 °C/11 mmHg (lit.) |
| Density | 1.014 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 195 °F |
| pka | 13.74±0.46(Predicted) |
| Water Solubility | Immiscible with water. |
| BRN | 1781709 |
Safety information for Diethyl tert-butylmalonate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids |
| Precautionary Statement Codes |
P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for Diethyl tert-butylmalonate
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