methyl 6-(bromomethyl)nicotinate
- CAS NO.：131803-48-0
- Empirical Formula: C8H8BrNO2
- Molecular Weight: 230.06
- MDL number: MFCD10566280
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:04:57
What is methyl 6-(bromomethyl)nicotinate?
The Uses of methyl 6-(bromomethyl)nicotinate
methyl 6-(bromomethyl)nicotinate is an organic reagent mainly used in chemical and scientific laboratory research.
Synthesis
methyl 6-(bromomethyl)nicotinate is synthesised using methyl 6-methylnicotinate as a raw material by chemical reaction. The specific synthesis steps are as follows:
0.471 g (1.0 equivalent) of N-bromosuccinimide and 64 mg (0.1 equivalent) of benzoyl peroxide are added to a solution of 0.4 g of the product obtained in the preceding Stage 1 in 15 ml of carbon tetrachloride. The solution is brought to reflux for 6 hours, then filtered and evaporated under reduced pressure. The residue is purified by chromatography on silica gel (dichloromethane/ethyl acetate: 95/5) to produce 0.262 g of the expected product. [ Yield: 43percent MS: MH+ 231].
Properties of methyl 6-(bromomethyl)nicotinate
| Boiling point: | 284.9±30.0℃ (760 Torr) |
| Density | 1.533±0.06 g/cm3 (20 ºC 760 Torr) |
| Flash point: | 126.1±24.6℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 1.40±0.22(Predicted) |
| form | solid |
| color | OFF WHITE |
Safety information for methyl 6-(bromomethyl)nicotinate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for methyl 6-(bromomethyl)nicotinate
methyl 6-(bromomethyl)nicotinate manufacturer
BTC Pharmaceuticals Technology India
New Products
1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 1-Benzhydrylazetane-3-carbonitrile 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2-(2-Chlorophenyl)glycine AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2'-Fluoroacetophenone METHANOL-D1(OD) N-ETHYL-D5-AMINE HYDROCHLORIDE BENZOIC ACID-D CHLOROFORM-D BENZENE-D6 TOLUENE-D3 2-Hydroxybutanenitrile 1-Benzylindolin-2-one Ethyl 2-bromo-3-oxobutanoate 4-(3-chloropropyl)morpholine 1-Benzylindoline-2,3-dione 3-Oxocyclobutanecarboxylic acid 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
You may like
-
Methyl 6-(bromomethyl)nicotinate 95% CAS 131803-48-0View Details
131803-48-0 -
Methyl 6-(Bromomethyl)Nicotinate,Cas No:131803-48-0View Details
131803-48-0 -
5-Bromo-2-chloro- benzoic acid 21739-92-4 98%View Details
21739-92-4 -
Guar Hydroxypropyltrimonium Chloride 98%View Details
65497-29-2 -
52092-43-0 2-Bromo-4-nitropyridine-N-oxide 98%View Details
52092-43-0 -
2,4,6-Trichloro-5-nitropyrimidine 98%View Details
4359-87-9 -
1-Methylpiperidine-4-thiol 1072-99-7 98%View Details
1072-99-7 -
68886-07-7 98%View Details
68886-07-7