Methyl 2-aminonicotinate

Synonym(s):Methyl 2-aminonicotinate

CAS NO.：14667-47-1
Empirical Formula: C7H8N2O2
Molecular Weight: 152.15
MDL number: MFCD00128872
EINECS: 681-092-5
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 06:03:20

What is Methyl 2-aminonicotinate?

Chemical properties

Off white powder

The Uses of Methyl 2-aminonicotinate

Methyl 2-Aminonicotinate is used to prepare 2-{4-[(3S)-Piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827)as a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors. It is also used to synthesize quinazolinone/quinazoline thione derivatives as phosphodiesterase 7 inhibitors.

Properties of Methyl 2-aminonicotinate

Melting point:	82-86 °C
Boiling point:	251.3±20.0 °C(Predicted)
Density	1.238±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
pka	4.71±0.36(Predicted)
color	White to Almost white
CAS DataBase Reference	14667-47-1(CAS DataBase Reference)

Safety information for Methyl 2-aminonicotinate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.