Methiothepin maleate
- CAS NO.：19728-88-2
- Empirical Formula: C24H28N2O4S2
- Molecular Weight: 472.62
- MDL number: MFCD00209930
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-11-04 17:01:56
What is Methiothepin maleate?
The Uses of Methiothepin maleate
Methiothepin Maleate exhibits anticonvulsant property and it is able to suppress pentylenetetrazol induced fos expression in zebrafish. In addition, Methiothepin Maleate is a 5-HT antagonist.
The Uses of Methiothepin maleate
Biochemical tool in serotonin receptor binding studies.
What are the applications of Application
Methiothepin maleate is a potent 5-HT2 and active 5-HT1 antagonist
Definition
ChEBI: A maleate salt obtained by reaction of methiothepin with one equivalent of maleic acid. Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types. Also displays ffinity for rodent 5-HT5B, 5-HT5A, 5-HT7 and 5-HT6 receptors (pK1 values are 6.6, 7.0, 8.4 and 8.7 respectively).
Properties of Methiothepin maleate
| Melting point: | 171-173° |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Soluble to 100 mM in DMSO |
| form | Powder |
Safety information for Methiothepin maleate
Computed Descriptors for Methiothepin maleate
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