Metaflumizone

Synonym(s):2′-[2-(4-Cyanophenyl)-1-(α,α,α-trifluoro-m-tolyl)ethylidene]-4-(trifluoromethoxy)carbanilohydrazide

CAS NO.：139968-49-3
Empirical Formula: C24H16F6N4O2
Molecular Weight: 506.4
MDL number: MFCD08690508
EINECS: 204-798-3
SAFETY DATA SHEET (SDS)
Update Date: 2026-06-03 11:24:09

What is Metaflumizone?

The Uses of Metaflumizone

Metaflumizone is a semicarbazone insecticide that works by blocking sodium channel in target insects resulting in paralyzation associated with blocking nerve activity. Metaflumizone is useful as a hea rtworm control treatment.

Veterinary Drugs and Treatments

Metaflumizone is a new insecticide used for the treatment and control of fleas on dogs and cats. It blocks the influx of sodium required to propagate a nerve impulse along the axon and dendrite of the neuron causing a reduction in feeding, loss of coordination, paralysis and death of the flea.

Properties of Metaflumizone

Density	1.34±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO (Slightly), Methanol (Slightly, Heated)
form	neat
pka	10.82±0.46(Predicted)
form	Solid
color	Light yellow to yellow
EPA Substance Registry System	Hydrazinecarboxamide, 2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]- (139968-49-3)

Safety information for Metaflumizone

Signal word	Warning
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H362:Reproductive toxicity, effects on or via lactation H373:Specific target organ toxicity, repeated exposure
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P263:Avoid contact during pregnancy/while nursing. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P308+P313:IF exposed or concerned: Get medical advice/attention.