Mes-PEG5- THP
- CAS NO.:145927-73-7
- Empirical Formula: C14H28O8S
- Molecular Weight: 356.43
- MDL number: MFCD29049413
- Update Date: 2025-12-15 16:23:17
What is Mes-PEG5- THP?
Biological Activity
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Mes-PEG5- THP
| form | Liquid |
| color | Light yellow to light brown |
Safety information for Mes-PEG5- THP
Computed Descriptors for Mes-PEG5- THP
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