Hydroxy-PEG3-Mes
- CAS NO.：139115-89-2
- Empirical Formula: C7H16O6S
- Molecular Weight: 228.26
- MDL number: MFCD22574814
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is Hydroxy-PEG3-Mes?
Biological Activity
Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Hydroxy-PEG3-Mes
| Boiling point: | 398.2±27.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| pka | 14.36±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Hydroxy-PEG3-Mes
Computed Descriptors for Hydroxy-PEG3-Mes
New Products
5-bromo-4-fluoro-2-nitrobenzaldehyde (R)-(-)-2-Amino-1-propanol Cyclobutanone Fmoc-OSu 1-(2-Chloroethyl)pyrrolidine Hydrochloride 2-Amino-2-(4-methylphenyl)acetic acid β-Bromostyrene Ethyl 3-phenylpropanoate Phenethyl cinnamate Dipropyl disulfide 4 pentyn 1 ol N-Vinylformamide Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 2-Butyn-1-oL 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine Pirtobrutinib intd. N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
![3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid](https://img.chemicalbook.in/CAS/20150408/GIF/1334286-77-9.gif)
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