Hydroxy-PEG3-Mes
- CAS NO.：139115-89-2
- Empirical Formula: C7H16O6S
- Molecular Weight: 228.26
- MDL number: MFCD22574814
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is Hydroxy-PEG3-Mes?
Biological Activity
Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of Hydroxy-PEG3-Mes
| Boiling point: | 398.2±27.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| pka | 14.36±0.10(Predicted) |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for Hydroxy-PEG3-Mes
Computed Descriptors for Hydroxy-PEG3-Mes
New Products
2-(2-Ethoxyphenoxy)ethyl bromide 1,3-Dibromo-2,2-dimethoxypropane 8-Bromo-7-(2-butynyl)-3-methyl xanthine 5-Chlorothiophene-2-carboxylic acid 8-Bromo-3-methyl xanthine Maleic hydrazide o-Anisaldehyde 4-Bromobenzaldehyde 3-Fluorobenzaldehyde 2-Chlorobenzaldehyde 3-Amino-3-(3-fluorophenyl)propanoic acid 1-Propyl-4-piperidone 2,3-Dihydro-5,6-dimethoxy-2-(4-piperidinylmethyl)-1H-inden-1-one hydrochloride 3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1h-benzo[d]imidazol-1-yl)piperidine-2,6-dione 2-Fluoro-6-iodobenzoic acid 3-Pyridineacrylic acid 1-Boc-4-cyanopiperidine ethyl 2-oxo-2,3,9,10-tetrahydro-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline-8(7H)-carboxylate Vardenafil Bis-sulphonamide(Dimer) Nitroso Irbesartan N-Nitroso Nortriptyline Sulfonic acid Impurity 2-(p-Tolyl)acetaldehyde 2,2-dibromo-1-cyclopropyl-2-(2-fluorophenyl)ethan-1-oneRelated products of tetrahydrofuran
![3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid](https://img.chemicalbook.in/CAS/20150408/GIF/1334286-77-9.gif)
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