3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
- CAS NO.：1334286-77-9
- Empirical Formula: C7H14O5
- Molecular Weight: 178.18
- MDL number: MFCD20646030
- Update Date: 2026-03-12 18:10:29
![3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid Structural](https://img.chemicalbook.in/CAS/20150408/GIF/1334286-77-9.gif)
What is 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid?
Description
Hydroxy-PEG2-acid sodium salt is a PEG linker containing a hydroxyl group with a terminal carboxylic acid (as sodium salt form). The free acid form is not stable due to the reaction of OH with PEG-COOH group to form polymer. The sodium salt form is stable for storage and shipping. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Properties of 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
| Boiling point: | 350.0±27.0 °C(Predicted) |
| Density | 1.196±0.06 g/cm3(Predicted) |
| solubility | Soluble in Water, DMSO, DMF |
| pka | 4.27±0.10(Predicted) |
| form | A liquid |
| color | Colorless to light yellow |
Safety information for 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P330:Rinse mouth. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for 3-[2-(2-Hydroxyethoxy)ethoxy]propanoic acid
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