Cysteamine bitartrate
- CAS NO.：27761-19-9
- Empirical Formula: C6H13NO6S
- Molecular Weight: 227.23
- MDL number: MFCD08277629
- EINECS: 248-641-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-14 10:24:48
What is Cysteamine bitartrate?
References
[1] Sujay Guha. “Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease.” Human molecular genetics (2019): 1837–1852.
Description
Cysteamine bitartrate is an amino thiol and a byproduct of the cysteine degradation pathway that is an FDA-approved therapy for the treatment of nephropathic cystinosis to decrease the accumulation of lysosomal cystine (the disulfide-linked form of cysteine) by engaging in disulfide exchange. In addition, cysteamine bitartrate has been postulated to have broader antioxidant properties potentially related to a distinct role in increasing cysteine availability to support the biosynthesis of the potent antioxidant molecule glutathione[1].
The Uses of Cysteamine bitartrate
Cysteamine bitartrate (CAS# 27761-19-9) treatment of cystinosis and other metabolic and neurodegenerative diseases.
Properties of Cysteamine bitartrate
| storage temp. | Store at -20°C |
| solubility | DMSO: 45 mg/mL (198.03 mM);Ethanol: Insoluble |
| Water Solubility | Water: 45 mg/mL (198.03 mM) |
| InChI | InChI=1/C4H6O6.C2H7NS/c5-1(3(7)8)2(6)4(9)10;3-1-2-4/h1-2,5-6H,(H,7,8)(H,9,10);4H,1-3H2/t1-,2-;/s3 |
Safety information for Cysteamine bitartrate
Computed Descriptors for Cysteamine bitartrate
| InChIKey | NSKJTUFFDRENDM-RZHFEHKBNA-N |
| SMILES | C(N)CS.[C@H](O)(C(=O)O)[C@@H](O)C(=O)O |&1:4,9,r| |
Cysteamine bitartrate manufacturer
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