Mandelic acid
Synonym(s):(R)-(-)-Mandelic acid;DL -Mandelic acid;D-Mandelic acid, D-α-Hydroxyphenylacetic acid;Racemic mandelic acid;(R)-α-Hydroxyphenylacetic acid
- CAS NO.：611-71-2
- Empirical Formula: C8H8O3
- Molecular Weight: 152.15
- MDL number: MFCD00064251
- EINECS: 210-276-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-20 10:51:09
What is Mandelic acid?
Definition
ChEBI: (R)-mandelic acid is the (R)-enantiomer of mandelic acid. It has a role as a human xenobiotic metabolite. It is a conjugate acid of a (R)-mandelate. It is an enantiomer of a (S)-mandelic acid.
Synthesis Reference(s)
The Journal of Organic Chemistry, 33, p. 2565, 1968 DOI: 10.1021/jo01270a105
Synthetic Communications, 18, p. 2141, 1988 DOI: 10.1080/00397918808068285
Safety
Mandelic acid is a great AHA option for all skin types but is a particularly wonderful option for sensitive skin due to its gentle nature.
Sources
Mandelic acid is an exfoliating alpha hydroxy acid (AHA) that may be derived from bitter almonds or synthetically created.
The Uses of Mandelic acid
Mandelic acid benefits skin primarily through exfoliation. Like other AHAs, it works to loosen the bonds between skin cells, allowing dead, dull cells to slough off and in the process, reveals radiant, healthy skin.
Properties of Mandelic acid
| Melting point: | 131-133 °C(lit.) |
| Boiling point: | 214.6°C (rough estimate) |
| alpha | -150 º (c=2.5, H2O) |
| Density | 1.1677 (rough estimate) |
| refractive index | -153.5 ° (C=1, H2O) |
| Flash point: | >190℃ |
| storage temp. | Store below +30°C. |
| solubility | 109.8g/l soluble |
| form | Crystalline Powder, Crystals or Flakes |
| pka | 3.37(at 25℃) |
| color | White to slightly yellow-beige |
| PH | 3.34(1 mM solution);2.75(10 mM solution);2.22(100 mM solution); |
| optical activity | [α]25/D 151°, c = 1 in ethanol |
| Water Solubility | It is partly soluble in water, freely soluble in isopropyl and ethyl alcohol. |
| Sensitive | Light Sensitive |
| BRN | 2691094 |
| Stability: | Stable, but light sensitive. Combustible. Incompatible with strong bases, strong oxidizing agents. |
| CAS DataBase Reference | 611-71-2(CAS DataBase Reference) |
| EPA Substance Registry System | Benzeneacetic acid, .alpha.-hydroxy-, (.alpha.R)- (611-71-2) |
Safety information for Mandelic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Mandelic acid
| InChIKey | IWYDHOAUDWTVEP-SSDOTTSWSA-N |
Mandelic acid manufacturer
JSK Chemicals
3Y
Phone:+91-9879767984
Whatsapp: +91-9879767970
product: 611-71-2 (R)-(-)-Mandelic acid, 98% 99%
R P Chemicals
Maharashtra
product: D-Mandelic Acid, Packaging Size: 1kg/05kg/25kg, Grade: Laboratory
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