Mal-PEG4-amine TFA salt
- CAS NO.：2512227-13-1
- Empirical Formula: C16H25F3N2O8
- Molecular Weight: 430.38
- MDL number: MFCD31920055
- Update Date: 2025-04-17 18:22:24
What is Mal-PEG4-amine TFA salt?
Biological Activity
Mal-PEG4-C2-NH2 TFA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Safety information for Mal-PEG4-amine TFA salt
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