Mafenide hydrochloride
Synonym(s):4-Homosulfanilamide;Mafenide;Marfanil
- CAS NO.：138-37-4
- Empirical Formula: C7H11ClN2O2S
- Molecular Weight: 222.69
- MDL number: MFCD00013005
- EINECS: 205-325-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is Mafenide hydrochloride?
The Uses of Mafenide hydrochloride
Antibacterial;Inhibitor of folic acid biosynthesis
Purification Methods
Crystallise the salt from dilute HCl or 95% EtOH and dry it in a vacuum at 100o. It is an antibacterial. [Miller et al. J Am Chem Soc 62 2099 1940, Bergeim & Barker J Am Chem Soc 66 1459 1944.] The sulfate salt has m 254-255o (from aqueous EtOH). [Beilstein 14 III 2223, 14 IV 2799.]
Properties of Mafenide hydrochloride
| Melting point: | 261-263 °C(lit.) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | neat |
| form | Solid |
| color | White |
| Merck | 13,5671 |
| CAS DataBase Reference | 138-37-4(CAS DataBase Reference) |
Safety information for Mafenide hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Mafenide hydrochloride
| InChIKey | SIACJRVYIPXFKS-UHFFFAOYSA-N |
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