LysoFP-NO2

CAS NO.：69408-75-9
Empirical Formula: C18H17N3O5
Molecular Weight: 355.34
Update Date: 2025-04-17 18:22:24

What is LysoFP-NO2?

Description

LysoFP-NO₂ is a turn-on fluorescent probe for carbon monoxide (CO) that localizes to the lysosome.¹ In the presence of lysosomal CO, lysoFP-NO₂ is transformed into lysoFP-NH₂, which is highly fluorescent. LysoFP-NO₂ is selective for CO over various reactive nitrogen, oxygen, and sulfur species. It displays excitation/emission maxima of 440/528 nm, respectively, and is not cytotoxic to HepG2 cells for up to five hours when used at a concentration of 30 μM.

References

1. Dhara, K., Lohar, S., Patra, A., et al. A new lysosome-targetable turn-on fluorogenic probe for carbon monoxide imaging in living cells Anal. Chem. 90(4),2933-2938(2018).

Properties of LysoFP-NO2

Melting point:	188-190 °C(Solv: ethanol (64-17-5))
Boiling point:	573.1±45.0 °C(Predicted)
Density	1.417±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Chloroform: 30 mg/ml
form	A crystalline solid
pka	6.53±0.10(Predicted)

Safety information for LysoFP-NO2

Computed Descriptors for LysoFP-NO2

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