LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
Synonym(s):des-Arg10-Kallidin
- CAS NO.：71800-36-7
- Empirical Formula: C50H73N13O11
- Molecular Weight: 1032.2
- MDL number: MFCD00079826
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-06-18 16:39:34
What is LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE?
The Uses of LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
[Lys-des-Arg9]-Bradykinin has been used as a B1R agonist to investigate the role of B1R in diabetes-induced secondary hemorrhage.
Biochem/physiol Actions
[Des-Arg10]-kallidin or [Lys-des-Arg9]-Bradykinin is a bradykinin B1 receptor agonist. It strongly upregulates the B1 receptor and is blocked by a specific protein kinase C inhibitor. The upregulation is correlated with the induction of transcription nuclear factor κB (NF-κB). Elevation of Lys-des[Arg9]–bradykinin because of airway inflammation in asthma patients is known to modify the immune responses. It affects the migration and production of interleukin-12 in monocyte-derived dendritic cells.
Storage
Store at -20°C
Properties of LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
| Density | 1.45±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| form | Powder |
| pka | 3.56±0.10(Predicted) |
| Water Solubility | Soluble to 1 mg/ml in water |
Safety information for LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
Computed Descriptors for LYS-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE
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![KALLIDIN, (DES-10-ARG) [3,4-PROLYL-3,4-3H(N)]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure3/GIF/CB5288629.gif)
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