LY 303511
Synonym(s):2-Piperazinyl-8-phenyl-4H-1-benzopyran-4-one, BRD2 Inhibitor V, BRD3 Inhibitor IV, BRD4 Inhibitor V;LY 303511 - CAS 154447-38-8 - Calbiochem
- CAS NO.：154447-38-8
- Empirical Formula: C19H18N2O2
- Molecular Weight: 306.36
- MDL number: MFCD03453556
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:20:29
What is LY 303511?
The Uses of LY 303511
LY 303511 is an inactive analog of the phosphoinositide 3-kinase inhibitor LY294002.
What are the applications of Application
LY 303511 is a negative control for PI 3-kinase inhibitors
Definition
ChEBI: 8-phenyl-2-(1-piperazinyl)-1-benzopyran-4-one is a N-arylpiperazine.
Biological Activity
Negative control compound with respect to LY 294004 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-onehydrochloride ) PI 3-kinase inhibitory activity. Blocks voltage-gated potassium (K v ) channels (IC 50 = 64.6 μ M) and inhibits IL-1 β -stimulated NF- κ B activation, attenuating MCP-1 expression. Anti-proliferative.
Properties of LY 303511
| Boiling point: | 496.1±45.0 °C(Predicted) |
| Density | 1.237±0.06 g/cm3(Predicted) |
| storage temp. | Store at +4°C |
| solubility | Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO |
| pka | 9.20±0.10(Predicted) |
| form | Amber solid |
Safety information for LY 303511
Computed Descriptors for LY 303511
New Products
Levothyroxine Impurity-F Montelukast EP Impurity-D/Montelukast USP Related Compound C Atorvastatin FXA Impurity/Atorvastatin Cyclic 6-Hydroxy Impurity Sodium Salt Isosulfan blue Keto N-Oxide Impurity Ivermectin Impurity F N-Nitroso des Methyl Tramadol/N-Nitroso-N-Desmethyl-Tramadol DL-beta-(3-Bromophenyl)alanine Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) N,N CARBONYL DIIMIDAZOLE (R)-BoroLeu-(+)-Pinanediol-CF3COOH 1,4-bis(methylsulfonyl)butane 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzene CSA (DL-10-Camphorsulfonic Acid) 2-Hydroxy-4-methylnicotinic acid 3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (2S)-1-((2S,3S)-3-(2-methylbutyl)-4-oxooxetan-2-yl)pentadecan-2-yl formylleucinate 1-(3,5-dichlorophenyl)-2,2,2-trifluoroethane-1-sulfonyl chloride S-(1-(3,5-dichlorophenyl)-2,2,2-trifluoroethyl) ethanethioateRelated products of tetrahydrofuran
You may like
-
674783-97-2 98+View Details
674783-97-2 -
H-D-TRP(FOR)-OH HCL 98+View Details
367453-01-8 -
DL-beta-(3-Bromophenyl)alanine 117391-50-1 98+View Details
117391-50-1 -
1923-70-2 Tetrabutylammonium perchlorate 98+View Details
1923-70-2 -
49830-37-7 98+View Details
49830-37-7 -
3-Amino-3-(4-fluorophenyl)propanoic acid 98+View Details
325-89-3 -
1428243-26-8 98+View Details
1428243-26-8 -
1-aminocyclopentane carbonitrile, HCl 98+View Details
16195-83-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.