LY 294002
- CAS NO.：934389-88-5
- Empirical Formula: C19H18ClNO3
- Molecular Weight: 343.80412
- MDL number: MFCD01530034
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is LY 294002?
The Uses of LY 294002
LY 294002 Hydrochloride is a highly selective inhibitor of Phosphatidylinositol 3-kinase (PI3K). It is a salt analogue of LY 294002 (L486590).
What are the applications of Application
LY-294,002 hydrochloride is a highly selective inhibitor of PI 3-kinase
General Description
LY-294,002 hydrochloride is a derivative of the flavonoid, quercetin and elicits higher inhibition on the enzyme phosphoinositide 3-kinase (PI3K). LY-294,002 inhibits nuclear factor kappa B signaling in macrophages. It elevates expression of autophagosomal protein LC3 and promotes apoptosis in gastric and nasopharyngeal cancer cells. LY-294,002 modulates action potential repolarization and improves myocyte contractility.
Storage
Room temperature
Properties of LY 294002
| storage temp. | 2-8°C |
| solubility | DMSO: >5mg/mL |
| form | solid |
| color | white to off-white |
Safety information for LY 294002
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for LY 294002
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