LY 2784544
Synonym(s):3-(4-Chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine;3-[(4-Chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)imidazo[1,2-b]pyridazin-6-amine;LY 2784544;LY-2784544
- CAS NO.：1229236-86-5
- Empirical Formula: C23H25ClFN7O
- Molecular Weight: 469.94
- MDL number: MFCD20482143
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-03 11:24:09
What is LY 2784544?
The Uses of LY 2784544
LY2784544 is a JAK2 inhibitor. LY2784544 may be used as a potential treatment for patients with myeloproliferative neoplasm.
What are the applications of Application
LY2784544 is a selective inhibitor of JAK2 mutant V617F
Definition
ChEBI: Gandotinib is a member of pyridazines.
Properties of LY 2784544
| Density | 1.45 |
| storage temp. | Store at -20°C |
| solubility | ≥23.5 mg/mL in DMSO; insoluble in H2O; ≥5.65 mg/mL in EtOH with gentle warming and ultrasonic |
| form | solid |
| pka | 14.12±0.10(Predicted) |
| color | Light yellow to yellow |
Safety information for LY 2784544
Computed Descriptors for LY 2784544
New Products
Cis-Tosylate Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 2,6-Dipicolic Acid 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-One Dibenzo[b,f][1,4]thiazepin-11(10H)-one N-BOC-piperidine-4-carboxylic acid 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine (±)-amino(2-fluorophenyl)acetic acid 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione MEHYL AMINE-D3.HCL METHANE SULFONIC ACID-D4 PHOSPORIC ACID-D3 85 W% IN D2O DEUTERIUM OXIDE FOR NMR TOLUENE-D3 BENZENE-D6 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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