LUMULA

Empirical Formula: C24H43NO4
Molecular Weight: 409.6
MDL number: MFCD05863948

What is LUMULA?

Description

Lumula is a hybrid eicosanoid analog that incorporates the docosanoid and prostamide features of unoprostone (Item No. 16680) and bimatoprost (17-phenyl trinor Prostaglandin F_2α ethyl amide; ), respectively, prostaglandin analogs that lack potency at the prostanoid FP receptor. Based on classical structure-activity relationships that have been established for prostanoid receptors, lumula is predicted to have low activity at these receptors. The N-ethyl amide prodrug moiety it inherits from bimatoprost is slow to hydrolyze and the lower side chain modifications inherited from unoprostone interfere with FP receptor binding. Lumula is intended for use as a negative control for testing mechanisms of unoprostone and bimatoprost activity.

What are the applications of Application

Lumula is used in the study of gaucoma

Safety information for LUMULA

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