LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)
- CAS NO.:95991-05-2
- Empirical Formula: C94H178N2O25P2
- Molecular Weight: 1798.37
- MDL number: MFCD07369021
- Update Date: 2025-01-27 09:38:02
What is LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)?
The Uses of LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)
Lipid A, diphosphoryl from?Escherichia coli?F583 (Rd mutant) has been used:
- to study the effect of various lipid A molecules on lung pericyte proliferation in vitro
- to test on THP-1 and J774A.1 cells for neopterin and nitrite formation respectively
- as lipopolysaccharides (LPS) derivatives in binding experiments
- to stimulate the spleen cells and as a mitogen stimulation for toll like receptor 4 (TLR4)
General Description
Lipid A is the fundamental structure of lipopolysaccharides (LPS), present in bacteria.
Biochem/physiol Actions
Lipid A is mainly essential for the robust immunostimulatory activities of lipopolysaccharides (LPS) in human. Lipid A is the hydrophobic domain of LPS helps in anchoring LPS to the plasma membrane of bacteria. It is immunologically active and an important constituent of LPS recognised by immune system.
Properties of LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)
| Density | 1.13±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 1.73±0.10(Predicted) |
Safety information for LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)
Computed Descriptors for LIPID A, DIPHOSPHORYL FROM ESCHERICHIA COLI F-583 (RD MUTANT)
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