Lenalidomide-PEG1-azide
- CAS NO.：2185795-67-7
- Empirical Formula: C17H18N6O5
- Molecular Weight: 386.37
- MDL number: MFCD34469882
- Update Date: 2026-05-28 03:51:32
What is Lenalidomide-PEG1-azide?
Biological Activity
Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 [1].
References
[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
Properties of Lenalidomide-PEG1-azide
| solubility | DMSO : 100 mg/mL (258.83 mM; Need ultrasonic) |
| form | Solid |
| color | Off-white to light yellow |
Safety information for Lenalidomide-PEG1-azide
Computed Descriptors for Lenalidomide-PEG1-azide
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