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HomeProduct name listLAVENDUSTIN C

LAVENDUSTIN C

LAVENDUSTIN C Structural

What is LAVENDUSTIN C?

Description

Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 μM. Lavendustin C also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of 0.5 and 0.2 μM, respectively. At a concentration of 10-150 μM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.

Chemical properties

Brown Solid

The Uses of LAVENDUSTIN C

Shows potent tyrosine kinase inhibitory activity.

The Uses of LAVENDUSTIN C

Shows potent tyrosine kinase inhibitory activity

Definition

ChEBI: 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid is an aromatic amine.

What are the applications of Application

Lavendustin C is an inhibitor of CaMKII

Properties of LAVENDUSTIN C

Melting point: 193-195°C dec.
Boiling point: 597.5±50.0 °C(Predicted)
Density  1.551±0.06 g/cm3(Predicted)
storage temp.  −20°C
solubility  DMSO: soluble
form  solid
pka 2.32±0.10(Predicted)
color  Light Beige to Brown
Stability: Hygroscopic

Safety information for LAVENDUSTIN C

Computed Descriptors for LAVENDUSTIN C

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