LAUROLITSINE
- CAS NO.：5890-18-6
- Empirical Formula: C18H19NO4
- Molecular Weight: 313.35
- MDL number: MFCD06809897
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-11 16:31:51
What is LAUROLITSINE?
Description
This noraporphiae alkaloid has been obtained from Litsea japonica and Neolitsea sericea and swells at 11 5-8°C before melting. It is dextrorotatory with [o:lbl + 102.5° (EtOH) and yields a picrate as yellow needles, m.p. 212°C (dec.) and a picrolonate, m.p. 239°C (dec.). The N-methyl derivative is identical with boldine.
The Uses of LAUROLITSINE
Laurolitsine is an alkaloid extracted from Polyalthia longifolia var. pendula.
Definition
ChEBI: An isoquinoline alkaloid that is noraporphine substituted by hydroxy groups at positions 2 and 9 and methoxy groups at positions 1 and 10. Isolated from Litsea glutinosa and Lindera chunii, exhibits inhibitory activity against HIV 1 integrase.
References
Nakasato, Nomura., Chem. Pharm. Bull., (Tokyo), 7, 780 (1959)
Kozuka., J. Ph arm. Soc., Japan, 82, 1567 (1962)
See also:
Johns, Lamberton., Austral. J. Chem., 20, 1277 (1967)
Properties of LAUROLITSINE
| Melting point: | 138-140 ºC |
| Boiling point: | 453.15°C (rough estimate) |
| Density | 1.313 |
| refractive index | 1.5100 (estimate) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Cryst. |
| pka | 9.81±0.20(Predicted) |
| color | Off-white to pink |
Safety information for LAUROLITSINE
Computed Descriptors for LAUROLITSINE
New Products
Hendecanoic acid 2-Amino-5-cyanopyridine 2-Bromo-5-cyanopyridine DL-3-Amino-3-(2-methoxyphenyl)propionic acid 3-Hydroxypropionitrile 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4,4-Diethoxybutanenitrile 5-Bromo-4-chloro-3-indolyl-β-D-galactopyranoside 6-(4-Amino-2,6-dichlorophenoxy)-4-isopropylpyridazin-3(2H)-one Tetracaine Hydrochloride Ep Grade 2,2,2-Trichloroethyl chloroformate 2-Bromo-6-fluoroaniline 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amine 2-Chloro-6-nitro benzothiazole 2-Aminobenzo[d]thiazol-4-ol Methyl 2-aminobutanoate hydrochloride 3-Fluoro-6-methylpicolinonitrile 1-(4-Aminopiperidin-1-yl)-3,3,3-trifluoropropan-1-one 5-chloro-2-(4-methoxybenzyl)-4-(trifluoromethyl)pyridazin-3(2H)-one 3-cyanocyclohexane-1-carboxylic acidRelated products of tetrahydrofuran
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