Lanoconazole
Synonym(s):2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile
- CAS NO.：101530-10-3
- Empirical Formula: C14H10ClN3S2
- Molecular Weight: 319.83
- MDL number: MFCD00865590
- EINECS: 635-180-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-30 20:12:30
What is Lanoconazole?
Description
Lanoconazole is a potent antifungal imidazole launched in Japan for the treatment of dermal mycoses. Lanoconazole is reported to be an inhibitor of ergosterol biosynthesis thus altering the ultra structure of the cell wall. It exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., Penici//ium spp., and Candida spp., being particularly active against Trichophyton spp.. It is considerably more potent than other agents of the same family such as bifonazole and clotrimazole. Clinical efficacy was demonstrated by remarkable improvements in skin symptoms of the patients with tinea pedis, tinea corporis and cruis, candidiasis or tinea versicolor.
Chemical properties
Light-Yellow Crystals
Originator
Nihon Nohyaku (Japan)
The Uses of Lanoconazole
Antifungal
The Uses of Lanoconazole
Antifungal.
What are the applications of Application
Lanoconazole is an antifungal compound
Definition
ChEBI: Lanoconazole is a conazole antifungal drug and an imidazole antifungal drug.
brand name
Astat
Properties of Lanoconazole
| Melting point: | 141.50C |
| Boiling point: | 477.6±55.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | neat |
| pka | 3.76±0.10(Predicted) |
| form | Solid |
| color | White |
| CAS DataBase Reference | 101530-10-3(CAS DataBase Reference) |
Safety information for Lanoconazole
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for Lanoconazole
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