L-SEPIAPTERIN
Synonym(s):S-(−)-2-Amino-7,8-dihydro-6-(2-hydroxy-1-oxopropyl)-4(1H)-pteridinone;L -Sepiapterin
- CAS NO.：17094-01-8
- Empirical Formula: C9H11N5O3
- Molecular Weight: 237.22
- MDL number: MFCD00210214
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is L-SEPIAPTERIN?
Chemical properties
yellow to orange powder
The Uses of L-SEPIAPTERIN
L-Sepiapterin serves as a substrate for BH4 synthesis via the pterin salvage pathway. It inhibits rat liver GTP cyclohydrolase with an IC50 value of approximately 25 μM. It can be used to circumvent the inhibition of pterin biosynthesis by 2,4-diamino-6-hydroxy pyrimidine.[Cayman Chemical]
The Uses of L-SEPIAPTERIN
Sepiapterin improved the endothelial dysfunction in SMA from db?/db mice by decreasing oxidative stress. Sepiapterin is commonly used in the study for treamtment of Type I Diabetes
The Uses of L-SEPIAPTERIN
Sepiapterin can be used to induce sequence-specific photolesions in double-stranded DNA.
What are the applications of Application
An intermediate in the salvage pathway of tetrahydrobiopterin
Definition
ChEBI: L-sepiapterin is a sepiapterin with L configuration.
General Description
Sepiapterin, a pteridine derivative, is a stable precursor of tetrahydrobiopterin (BH4). It is a yellow pigment found in sepia mutant of Drosophila melanogaster and lemon Bombyx mori mutant (silkworm).
Biochem/physiol Actions
Cofactor of nitric oxide synthase; intracellularly converted to tetrahydro-biopterin leading to the stimulation of nitric oxide.
Properties of L-SEPIAPTERIN
| Melting point: | >270 °C (dec.) |
| Boiling point: | 448.1±55.0 °C(Predicted) |
| Density | 1.86±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO: 27 mg/mL |
| form | solid |
| pka | 12.33±0.20(Predicted) |
| color | yellow |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 17094-01-8 |
Safety information for L-SEPIAPTERIN
Computed Descriptors for L-SEPIAPTERIN
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline 5-Hydroxy-3,9-dimethyl-7H-benzo[c]fluoren-7-one Methyl 4-(acetyloxy)-6-methoxy-1-(4-methoxyphenyl)-2naphthalenecarboxylate 4-Hydroxy-6,7-dimethoxy-1-phenyl-2naphthalenecarboxylic acid (3,5-Dibromophenyl)[4-(trifluoromethyl)phenyl]methanone (4-butoxyphenyl)(4-fluorophenyl)methanone (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide 4-Ethyl-4-hydroxy-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione (E)-N'-(2-cyano-4-nitrophenyl)- N,N-dimethylformimidamide 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid Benzyl-N,4-dimethylpiperidine-3- amine dihydrochloride 5-bromopyridin-2-amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
You may like
-
151239-47-3 98+View Details
151239-47-3 -
4-Hydroxy-6-methyl-1-(4-methylphenyl)-2naphthalenecarboxylic acid 98+View Details
101894-09-1 -
83883-25-4 98+View Details
83883-25-4 -
(3,5-dibromophenyl)(4-methoxyphenyl)methanone 1991533-97-1 98+View Details
1991533-97-1 -
329786-30-3 98+View Details
329786-30-3 -
54598-15-1 4,5,7-Trimethyl-2(1H)-quinolinone 98+View Details
54598-15-1 -
4-(6-HYDROXYHEXYLOXY)BENZOIC ACID 83883-25-4 98+View Details
83883-25-4 -
2-[4-(1,1-Dimethylethyl)-2-naphthalenyl]-4,4,5,5tetramethyl-1,3,2-dioxaborolane 98+View Details
2217657-10-6