L-Lysine dihydrochloride

Synonym(s):(S)-2,6-Diaminohexanoic acid dihydrochloride

CAS NO.：657-26-1
Empirical Formula: C6H16Cl2N2O2
Molecular Weight: 219.11
MDL number: MFCD00066389
EINECS: 211-518-3
SAFETY DATA SHEET (SDS)
Update Date: 2025-09-29 14:31:13

What is L-Lysine dihydrochloride?

Chemical properties

white to very light yellow crystalline powder

The Uses of L-Lysine dihydrochloride

Synthesis of hyperbranched polylysine using the N-hydroxysuccinimide ester of L-lysine dihydrochloride as AB 2 building block. The histidine and lysine standards were prepared from L-histidine monohydro- chloride and L-lysine dihydrochloride respectively. L-Homocitrulline-The copper complex was prepared from L-lysine dihydrochloride in 80 to 86 per cent yields.

What are the applications of Application

L-Lysine dihydrochloride is an essential proteinogenic α amino acid

Purification Methods

Crystallise it from MeOH, in the presence of excess HCl, by adding diethyl ether. [Yoneya J Biochem (Tokyo) 38 343 1951, Kearley & Ingersoll J Am Chem Soc 73 5783 1951, Beilstein 4 IV 2717.]

Properties of L-Lysine dihydrochloride

Melting point:	200-206 °C(lit.)
alpha	14 º (c=2, water 18 ºC)
refractive index	15 ° (C=2, H2O)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	Crystalline Powder
color	White to very light yellow
Water Solubility	Soluble in water (100 mg/ml).
Sensitive	Hygroscopic
Merck	14,5636
BRN	4539715
CAS DataBase Reference	657-26-1(CAS DataBase Reference)
EPA Substance Registry System	Lysine dihydrochloride (657-26-1)

Safety information for L-Lysine dihydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.