L-Histidine hydrochloride

CAS NO.：645-35-2
Empirical Formula: C6H10ClN3O2
Molecular Weight: 191.62
MDL number: MFCD00064556
EINECS: 211-438-9
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 03:12:03

What is L-Histidine hydrochloride?

Description

L-Histidine hydrochloride can undergo racemization due to heating in water, leading to the formation of DL-histidine. It can be used as a supplement in conditions of riboflavin vitamin deficiency.

Chemical properties

White needles, plates, or crystalline powder; slightly bitter taste. Decomp 250C. Sol in water; insol in alc, ether.

The Uses of L-Histidine hydrochloride

Amino acid.

Flammability and Explosibility

Not classified

Properties of L-Histidine hydrochloride

Melting point:	243-244 °C(Solv: ethanol (64-17-5))
Density	1.472[at 20℃]
vapor pressure	0Pa at 20℃
storage temp.	Inert atmosphere,2-8°C
form	Crystalline
Water Solubility	149.55g/L at 20℃
BRN	4168261
InChI	InChI=1/C6H9N3O2.ClH/c7-5(6(10)11)1-4-2-8-3-9-4;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H/t5-;/s3
CAS DataBase Reference	645-35-2(CAS DataBase Reference)
EPA Substance Registry System	L-Histidine, monohydrochloride (645-35-2)

Safety information for L-Histidine hydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.