L-Dithiothreitol
Synonym(s):(−)-Cleland’s Reagent;(2R,3R)-1,4-Dimercapto-2,3-butanediol;L -DTT;Cleland reagent chiral
- CAS NO.：16096-97-2
- Empirical Formula: C4H10O2S2
- Molecular Weight: 154.25
- MDL number: MFCD00064305
- EINECS: 240-263-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:53:34
What is L-Dithiothreitol?
Chemical properties
white crystalline powder
The Uses of L-Dithiothreitol
L-DTT [(2R,3R)-1,4-dimercapto-2,3-butanediol; L-dithiothreitol], a chiral bidentate dithiol with two stereogenic centers, may be used in chiroptical response research. L-DDT is proposed as a stereoselective reducing agent for disulfide bridges in complex molecules.
What are the applications of Application
L-1,4-Dithiothreitol is a stereoselective reducing agent for disulfide bridges in complex molecules
Definition
ChEBI: L-1,4-dithiothreitol is a 1,4-dithiothreitol. It is an enantiomer of a D-1,4-dithiothreitol.
Properties of L-Dithiothreitol
| Melting point: | 51 °C |
| Boiling point: | 247.65°C (rough estimate) |
| Density | 1.156 (estimate) |
| refractive index | 26 ° (C=2.5, MeOH) |
| Flash point: | 110 °C |
| storage temp. | -20°C |
| solubility | H2O: soluble50mg/mL, clear to hazy, colorless |
| form | solid |
| pka | 9.28±0.10(Predicted) |
| color | White to Almost white |
| BRN | 2036371 |
| CAS DataBase Reference | 16096-97-2(CAS DataBase Reference) |
Safety information for L-Dithiothreitol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for L-Dithiothreitol
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