L 741626
Synonym(s):Dopamine D₂ Receptor Antagonist, L-741,626, L-741626, L741626;L-741,626 - CAS 81226-60-0 - Calbiochem
- CAS NO.：81226-60-0
- Empirical Formula: C20H21ClN2O
- Molecular Weight: 340.85
- MDL number: MFCD00953632
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-03 11:24:09
What is L 741626?
The Uses of L 741626
L-741,626 is a selective D2DR inhibitor. Also, it is a G protein-coupled receptors antagonists and inverse agonists.
The Uses of L 741626
L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.
What are the applications of Application
L-741,626 is a selective D2DR inhibitor
Definition
ChEBI: 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol is a member of piperidines.
Hazard
A poison.
Biochem/physiol Actions
L-741,626 is a selective dopamine (D2) receptor antagonist.
Storage
Store at RT
Properties of L 741626
| Boiling point: | 548.8±50.0 °C(Predicted) |
| Density | 1.311±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: ≥20mg/mL |
| form | powder |
| pka | 13.87±0.20(Predicted) |
| color | white to beige |
Safety information for L 741626
Computed Descriptors for L 741626
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